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TSPAN12 is overexpressed in NSCLC via p53 inhibition and promotes NSCLC cell growth in vitro and in vivo

BACKGROUND: Tetraspanin 12 (TSPAN12), a member of the phylogenetically ancient tetraspanin family, is linked to impaired vascularization of the eye called familial exudative vitreoretinopathy, while the functional role of TSPAN12 in lung cancer has not been well characterized. RESULTS: In our study,...

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Detalles Bibliográficos
Autores principales: Hu, Zhongwu, Hou, Daorong, Wang, Xiaowei, You, Zhenbing, Cao, Xiufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840276/
https://www.ncbi.nlm.nih.gov/pubmed/29535534
http://dx.doi.org/10.2147/OTT.S155620