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MiR34 inhibition induces human heart progenitor proliferation

MiR34 involvement in myocardial injury repair and ageing has been well documented in mouse model. Our aim was to establish whether the inhibition of miR34 expression through locked nucleic acid (LNA) could be used as a pharmacological intervention to enhance human heart repair. Cardiac progenitor ce...

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Detalles Bibliográficos
Autores principales: Iannolo, Gioacchin, Sciuto, Maria Rita, Raffa, Giuseppe Maria, Pilato, Michele, Conaldi, Pier Giulio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840309/
https://www.ncbi.nlm.nih.gov/pubmed/29511160
http://dx.doi.org/10.1038/s41419-018-0400-9