Single-cell RNA sequencing reveals developmental heterogeneity of blastomeres during major genome activation in bovine embryos

Embryonic development is initially controlled by maternal RNAs and proteins stored in the oocyte, until gene products gradually generated by the embryo itself take over. Major embryonic genome activation (EGA) in bovine embryos occurs at the eight- to 16-cell stage. Morphological observations, such...

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Detalles Bibliográficos
Autores principales: Lavagi, Ilaria, Krebs, Stefan, Simmet, Kilian, Beck, Andrea, Zakhartchenko, Valeri, Wolf, Eckhard, Blum, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840315/
https://www.ncbi.nlm.nih.gov/pubmed/29511234
http://dx.doi.org/10.1038/s41598-018-22248-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840315/
https://www.ncbi.nlm.nih.gov/pubmed/29511234
http://dx.doi.org/10.1038/s41598-018-22248-2

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