Patient-derived conditionally reprogrammed cells maintain intra-tumor genetic heterogeneity

Preclinical in vitro models provide an essential tool to study cancer cell biology as well as aid in translational research, including drug target identification and drug discovery efforts. For any model to be clinically relevant, it needs to recapitulate the biology and cell heterogeneity of the pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Correa, Bruna R. S., Hu, Joanna, Penalva, Luiz O. F., Schlegel, Richard, Rimm, David L., Galante, Pedro A. F., Agarwal, Seema
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840339/
https://www.ncbi.nlm.nih.gov/pubmed/29511269
http://dx.doi.org/10.1038/s41598-018-22427-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840339/
https://www.ncbi.nlm.nih.gov/pubmed/29511269
http://dx.doi.org/10.1038/s41598-018-22427-1

Ejemplares similares