Cytochrome c speeds up caspase cascade activation by blocking 14-3-3ε-dependent Apaf-1 inhibition

Apoptosis is a highly regulated form of programmed cell death, essential to the development and homeostasis of multicellular organisms. Cytochrome c is a central figure in the activation of the apoptotic intrinsic pathway, thereby activating the caspase cascade through its interaction with Apaf-1. O...

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Detalles Bibliográficos
Autores principales: Elena-Real, Carlos A., Díaz-Quintana, Antonio, González-Arzola, Katiuska, Velázquez-Campoy, Adrián, Orzáez, Mar, López-Rivas, Abelardo, Gil-Caballero, Sergio, De la Rosa, Miguel Á., Díaz-Moreno, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840378/
https://www.ncbi.nlm.nih.gov/pubmed/29511177
http://dx.doi.org/10.1038/s41419-018-0408-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840378/
https://www.ncbi.nlm.nih.gov/pubmed/29511177
http://dx.doi.org/10.1038/s41419-018-0408-1

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