Application of maltose as energy source in protein-free CHO-K1 culture to improve the production of recombinant monoclonal antibody

Oligosaccharides are generally considered to be un-utilized for growth of mammalian cells because their permeability across the cell membrane is low. However, in our previous study, we discovered that CHO and HEK293 cells consume maltose in culture media without serum and glucose. This is interestin...

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Detalles Bibliográficos
Autores principales: Leong, Dawn Sow Zong, Teo, Brian Kah Hui, Tan, Janice Gek Ling, Kamari, Hayati, Yang, Yuan Sheng, Zhang, Peiqing, Ng, Say Kong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840386/
https://www.ncbi.nlm.nih.gov/pubmed/29511312
http://dx.doi.org/10.1038/s41598-018-22490-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840386/
https://www.ncbi.nlm.nih.gov/pubmed/29511312
http://dx.doi.org/10.1038/s41598-018-22490-8

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