Inhibition of Drp1/Fis1 interaction slows progression of amyotrophic lateral sclerosis

Bioenergetic failure and oxidative stress are common pathological hallmarks of amyotrophic lateral sclerosis (ALS), but whether these could be targeted effectively for novel therapeutic intervention needs to be determined. One of the reported contributors to ALS pathology is mitochondrial dysfunctio...

Descripción completa

Detalles Bibliográficos
Autores principales: Joshi, Amit U, Saw, Nay L, Vogel, Hannes, Cunnigham, Anna D, Shamloo, Mehrdad, Mochly‐Rosen, Daria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840540/
https://www.ncbi.nlm.nih.gov/pubmed/29335339
http://dx.doi.org/10.15252/emmm.201708166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840540/
https://www.ncbi.nlm.nih.gov/pubmed/29335339
http://dx.doi.org/10.15252/emmm.201708166

Ejemplares similares