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Loss of kallikrein‐related peptidase 7 exacerbates amyloid pathology in Alzheimer's disease model mice

Deposition of amyloid‐β (Aβ) as senile plaques is one of the pathological hallmarks in the brains of Alzheimer's disease (AD) patients. In addition, glial activation has been found in AD brains, although the precise pathological role of astrocytes remains unclear. Here, we identified kallikrein...

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Detalles Bibliográficos
Autores principales: Kidana, Kiwami, Tatebe, Takuya, Ito, Kaori, Hara, Norikazu, Kakita, Akiyoshi, Saito, Takashi, Takatori, Sho, Ouchi, Yasuyoshi, Ikeuchi, Takeshi, Makino, Mitsuhiro, Saido, Takaomi C, Akishita, Masahiro, Iwatsubo, Takeshi, Hori, Yukiko, Tomita, Taisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840542/
https://www.ncbi.nlm.nih.gov/pubmed/29311134
http://dx.doi.org/10.15252/emmm.201708184