Atorvastatin inhibits osteoclast differentiation by suppressing NF-κB and MAPK signaling during IL-1β-induced osteoclastogenesis

BACKGROUND/AIMS: To define the effect of statins on interleukin 1β (IL-1β)-induced osteoclastogenesis and elucidate the underlying mechanisms. METHODS: Bone marrow cells were obtained from 5-week-old male ICR (Institute for Cancer Research) mice, and they were cultured to differentiate them into ost...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Won-Seok, Lee, Eun-Gyeong, Sung, Myung-Soon, Choi, Yun-Jung, Yoo, Wan-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Internal Medicine 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840582/
https://www.ncbi.nlm.nih.gov/pubmed/28352062
http://dx.doi.org/10.3904/kjim.2015.244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840582/
https://www.ncbi.nlm.nih.gov/pubmed/28352062
http://dx.doi.org/10.3904/kjim.2015.244

Ejemplares similares