Sorafenib inhibited cell growth through the MEK/ERK signaling pathway in acute promyelocytic leukemia cells

The present study assessed the mechanism underlying the effect of sorafenib on the proliferation and apoptosis of the acute promyelocytic leukemia (APL) cell line NB4. NB4 cells were treated with different concentrations of sorafenib (0, 1.5, 3, 6, and 12 µM) for 24, 48 and 72 h. Cell proliferation,...

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Detalles Bibliográficos
Autores principales: Zhang, Yunjie, Li, Gangcan, Liu, Xin, Song, Yanping, Xie, Jia, Li, Guang, Ren, Jingjing, Wang, Hao, Mou, Jiao, Dai, Jinqian, Liu, Feng, Guo, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840677/
https://www.ncbi.nlm.nih.gov/pubmed/29552199
http://dx.doi.org/10.3892/ol.2018.8010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840677/
https://www.ncbi.nlm.nih.gov/pubmed/29552199
http://dx.doi.org/10.3892/ol.2018.8010

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