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Effect of HK2, PKM2 and LDHA on Cetuximab efficacy in metastatic colorectal cancer

Although hexokinase (HK) 2, pyruvate kinase muscle (PKM) isozyme 2 and lactate dehydrogenase (LDH) A predict the efficacy of medicines in various solid tumors, their ability to predict the efficacy of cetuximab in metastatic colorectal cancer (mCRC) remains unclear. mCRC patients with pathological s...

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Detalles Bibliográficos
Autores principales: Wang, Haohua, Peng, Roujun, Chen, Xiuxing, Jia, Rui, Huang, Chunyue, Huang, Yuanyuan, Xia, Liangping, Guo, Guifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840691/
https://www.ncbi.nlm.nih.gov/pubmed/29552193
http://dx.doi.org/10.3892/ol.2018.8005