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Dynamic quantitative detection of ABC transporter family promoter methylation by MS-HRM for predicting MDR in pancreatic cancer

The main focus of the present study was to evaluate whether ABC transporter family promoter methylation predicted multidrug resistance in gemcitabine-resistant cancer cell lines (BxPC-3/Gem and PANC-1/Gem). Using low concentrations of gemcitabine, the cell lines acquired drug resistance with differe...

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Detalles Bibliográficos
Autores principales: Yao, Lie, Gu, Jichun, Mao, Yishen, Zhang, Xinju, Wang, Xiaoyi, Jin, Chen, Fu, Deliang, Li, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840752/
https://www.ncbi.nlm.nih.gov/pubmed/29552197
http://dx.doi.org/10.3892/ol.2018.8041