Loss of expression rather than cytoplasmic mislocalization of RUNX3 predicts worse outcome in non-small cell lung cancer

Functional inactivation of human runt-related transcription factor 3 (RUNX3) through mutation or epigenetic silencing has been well-documented in many cancerous entities. In addition to gene mutation and promoter hypermethylation, cytoplasmic mislocalization has emerged as another major manifestatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Xiaohui, Deng, Yujie, Shi, Yi, Zhu, Weifeng, Cai, Yibin, Xu, Chunwei, Zhu, Kunshou, Zheng, Xiongwei, Chen, Gang, Xie, Qi, Weng, Guoxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840764/
https://www.ncbi.nlm.nih.gov/pubmed/29545901
http://dx.doi.org/10.3892/ol.2018.7993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840764/
https://www.ncbi.nlm.nih.gov/pubmed/29545901
http://dx.doi.org/10.3892/ol.2018.7993

Ejemplares similares