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The hypoxic tumor microenvironment in vivo selects the cancer stem cell fate of breast cancer cells

BACKGROUND: Tumor hypoxia is an independent prognostic factor associated with poor patient survival. Emerging evidence suggests that hypoxia can potentially maintain or enhance the stem cell phenotype of both normal stem cells and cancer cells. However, it remains to be determined whether cell fate...

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Detalles Bibliográficos
Autores principales: Kim, Hoon, Lin, Qun, Glazer, Peter M., Yun, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840770/
https://www.ncbi.nlm.nih.gov/pubmed/29510720
http://dx.doi.org/10.1186/s13058-018-0944-8