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The hypoxic tumor microenvironment in vivo selects the cancer stem cell fate of breast cancer cells
BACKGROUND: Tumor hypoxia is an independent prognostic factor associated with poor patient survival. Emerging evidence suggests that hypoxia can potentially maintain or enhance the stem cell phenotype of both normal stem cells and cancer cells. However, it remains to be determined whether cell fate...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840770/ https://www.ncbi.nlm.nih.gov/pubmed/29510720 http://dx.doi.org/10.1186/s13058-018-0944-8 |