An RNAi screen of Rho signalling networks identifies RhoH as a regulator of Rac1 in prostate cancer cell migration

BACKGROUND: Cell migration is essential for development and tissue repair, but it also contributes to disease. Rho GTPases regulate cell migration, but a comprehensive analysis of how each Rho signalling component affects migration has not been carried out. RESULTS: Through an RNA interference scree...

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Detalles Bibliográficos
Autores principales: Tajadura-Ortega, Virginia, Garg, Ritu, Allen, Richard, Owczarek, Claudia, Bright, Michael D., Kean, Samuel, Mohd-Noor, Aisyah, Grigoriadis, Anita, Elston, Timothy C., Hahn, Klaus M., Ridley, Anne J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840776/
https://www.ncbi.nlm.nih.gov/pubmed/29510700
http://dx.doi.org/10.1186/s12915-018-0489-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840776/
https://www.ncbi.nlm.nih.gov/pubmed/29510700
http://dx.doi.org/10.1186/s12915-018-0489-4

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