Aberrant STAT phosphorylation signaling in peripheral blood mononuclear cells from multiple sclerosis patients

BACKGROUND: Multiple sclerosis (MS) is characterized by increased activation of peripheral blood mononuclear cells (PBMCs), linked to perturbations in the phosphorylation of signaling proteins. METHODS: We developed a phosphoflow cytometry protocol to assess the levels of 11 phosphorylated nuclear p...

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Detalles Bibliográficos
Autores principales: Canto, Ester, Isobe, Noriko, Didonna, Alessandro, Hauser, Stephen L., Oksenberg, Jorge R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840794/
https://www.ncbi.nlm.nih.gov/pubmed/29514694
http://dx.doi.org/10.1186/s12974-018-1105-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840794/
https://www.ncbi.nlm.nih.gov/pubmed/29514694
http://dx.doi.org/10.1186/s12974-018-1105-9

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