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Glial and tissue-specific regulation of Kynurenine Pathway dioxygenases by acute stress of mice

Stressors activate the hypothalamic-pituitary-adrenal (HPA) axis and immune system eliciting changes in cognitive function, mood and anxiety. An important link between stress and altered behavior is stimulation of the Kynurenine Pathway which generates neuroactive and immunomodulatory kynurenines. T...

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Detalles Bibliográficos
Autores principales: Dostal, Carlos R., Carson Sulzer, Megan, Kelley, Keith W., Freund, Gregory G., McCusker, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840960/
https://www.ncbi.nlm.nih.gov/pubmed/29520368
http://dx.doi.org/10.1016/j.ynstr.2017.02.002