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In silico Design, and In vitro Expression of a Fusion Protein Encoding Brucella abortus L7/L12 and SOmp2b Antigens

BACKGROUND: L7/L12 is a protective antigen conserved in main Brucella pathogens and is considered as potential vaccine candidate. Outer membrane protein 2b is an immunogen conserved in all Brucella pathogens. MATERIALS AND METHODS: The purpose of the current study was to in silico design a L7/L12-SO...

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Detalles Bibliográficos
Autores principales: Golshani, Maryam, Ghasemian, Melina, Gheibi, Nematollah, Bouzari, Saeid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840964/
https://www.ncbi.nlm.nih.gov/pubmed/29531919
http://dx.doi.org/10.4103/abr.abr_10_17