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Clinical Aspects of Microsatellite Instability Testing in Colorectal Cancer

Microsatellite instability (MSI) is a molecular hallmark for some colorectal cancers (CRCs) in which short tandem repeats are prone to mutations along with DNA sequences. It is due to DNA-mismatch-repair system deficiency because of a germline/somatic mutation in mismatch-repair (MMR) genes. The ger...

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Detalles Bibliográficos
Autores principales: Zeinalian, Mehrdad, Hashemzadeh-Chaleshtori, Morteza, Salehi, Rasoul, Emami, Mohammad Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841008/
https://www.ncbi.nlm.nih.gov/pubmed/29531926
http://dx.doi.org/10.4103/abr.abr_185_16