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Imaging and Methotrexate Response Monitoring of Systemic Inflammation in Arthritic Rats Employing the Macrophage PET Tracer [(18)F]Fluoro-PEG-Folate

BACKGROUND: In rheumatoid arthritis, articular inflammation is a hallmark of disease, while the involvement of extra-articular tissues is less well defined. Here, we examined the feasibility of PET imaging with the macrophage tracer [(18)F]fluoro-PEG-folate, targeting folate receptor β (FRβ), to mon...

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Detalles Bibliográficos
Autores principales: Chandrupatla, Durga M. S. H., Jansen, Gerrit, Mantel, Elise, Low, Philip S., Matsuyama, Takami, Musters, René P., Windhorst, Albert D., Lammertsma, Adriaan A., Molthoff, Carla F. M., van der Laken, Conny J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841060/
https://www.ncbi.nlm.nih.gov/pubmed/29681783
http://dx.doi.org/10.1155/2018/8092781