Metformin Regulating miR-34a Pathway to Inhibit Egr1 in Rat Mesangial Cells Cultured with High Glucose

BACKGROUND: Activating AMPKα negatively regulates Egr1 to inhibit inflammatory cytokines in high glucose. miR-34a inhibition increases phosphorylated AMPKα through mediating SIRT1 to suppress the development of fatty liver. AIM OF THE STUDY: To clarify the function of Egr1 on the inflammation and fi...

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Detalles Bibliográficos
Autores principales: Wu, Can, Qin, Ningning, Ren, Huiwen, Yang, Min, Liu, Shuang, Wang, Qiuyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841108/
https://www.ncbi.nlm.nih.gov/pubmed/29681936
http://dx.doi.org/10.1155/2018/6462793

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841108/
https://www.ncbi.nlm.nih.gov/pubmed/29681936
http://dx.doi.org/10.1155/2018/6462793

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