Cargando…

Metformin Regulating miR-34a Pathway to Inhibit Egr1 in Rat Mesangial Cells Cultured with High Glucose

BACKGROUND: Activating AMPKα negatively regulates Egr1 to inhibit inflammatory cytokines in high glucose. miR-34a inhibition increases phosphorylated AMPKα through mediating SIRT1 to suppress the development of fatty liver. AIM OF THE STUDY: To clarify the function of Egr1 on the inflammation and fi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Can, Qin, Ningning, Ren, Huiwen, Yang, Min, Liu, Shuang, Wang, Qiuyue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841108/ https://www.ncbi.nlm.nih.gov/pubmed/29681936 http://dx.doi.org/10.1155/2018/6462793

Ejemplares similares

miR-34a regulates mesangial cell proliferation via the PDGFR-β/Ras-MAPK signaling pathway
por: Chen, Dapeng, et al.
Publicado: (2014)

HCMV miR-US22 down-regulation of EGR-1 regulates CD34+ hematopoietic progenitor cell proliferation and viral reactivation
por: Mikell, Iliyana, et al.
Publicado: (2019)

Methylation of miR-34a, miR-34b/c, miR-124-1 and miR-203 in Ph-negative myeloproliferative neoplasms
por: Chim, Chor Sang, et al.
Publicado: (2011)

Quantitative Proteomic Analysis of Gene Regulation by miR-34a and miR-34c
por: Ebner, Olivia A., et al.
Publicado: (2014)

miR302 regulates SNAI1 expression to control mesangial cell plasticity
por: De Chiara, L., et al.
Publicado: (2017)

Corrigendum: miR302 regulates SNAI1 expression to control mesangial cell plasticity
por: De Chiara, Letizia, et al.
Publicado: (2017)

miR-25 Regulates Gastric Cancer Cell Growth and Apoptosis by Targeting EGR2
por: Yang, Liuqing, et al.
Publicado: (2021)

Metformin Increases Sensitivity of Melanoma Cells to Cisplatin by Blocking Exosomal-Mediated miR-34a Secretion
por: Ge, Lan, et al.
Publicado: (2021)

MiR-34a and miR-34b/c have distinct effects on the suppression of lung adenocarcinomas
por: Kim, Jeong Seon, et al.
Publicado: (2019)

Analysis of the miR-34 family functions in breast cancer reveals annotation error of miR-34b
por: Engkvist, M. E., et al.
Publicado: (2017)

In Vivo Analysis of miR-34a Regulated Glucose Metabolism Related Genes in Megalobrama amblycephala
por: Miao, Ling-Hong, et al.
Publicado: (2018)

Metformin decreases miR-122, miR-223 and miR-29a in women with polycystic ovary syndrome
por: Udesen, Pernille Bækgaard, et al.
Publicado: (2020)

miR-34: from bench to bedside
por: Agostini, Massimiliano, et al.
Publicado: (2014)

Axl Expression in Renal Mesangial Cells Is Regulated by Sp1, Ap1, MZF1, and Ep300, and the IL-6/miR-34a Pathway
por: Adams, David E., et al.
Publicado: (2022)

MiR-34a and miR-206 act as novel prognostic and therapy biomarkers in cervical cancer
por: Chen, Ai-Hua, et al.
Publicado: (2017)

Differential effects of miR-34c-3p and miR-34c-5p on the proliferation, apoptosis and invasion of glioma cells
por: WU, ZHENDONG, et al.
Publicado: (2013)

miR-454-3p promotes of human glioma cell growth by targeting EGR3
por: Shen, Guoliang, et al.
Publicado: (2019)

The HMGA1 Pseudogene 7 Induces miR-483 and miR-675 Upregulation by Activating Egr1 through a ceRNA Mechanism
por: De Martino, Marco, et al.
Publicado: (2017)

Effects of Dangguibuxue decoction on rat glomerular mesangial cells cultured under high glucose conditions
por: Ren, Xiao-Dan, et al.
Publicado: (2017)

Hyperoside Alleviates High Glucose-Induced Proliferation of Mesangial Cells through the Inhibition of the ERK/CREB/miRNA-34a Signaling Pathway
por: Zhang, Le, et al.
Publicado: (2020)

MiR-21, miR-34a, miR-198 and miR-217 as diagnostic and prognostic biomarkers for chronic pancreatitis and pancreatic ductal adenocarcinoma
por: Vychytilova-Faltejskova, Petra, et al.
Publicado: (2015)

The Mechanism of miR-155/miR-15b Axis Contributed to Apoptosis of CD34+ Cells by Upregulation of PD-L1 in Myelodysplastic Syndromes
por: Cao, MeiWan, et al.
Publicado: (2023)

Exosome and Melatonin Additively Attenuates Inflammation by Transferring miR-34a, miR-124, and miR-135b
por: Heo, June Seok, et al.
Publicado: (2020)

Circulating miRNAs miR-34a and miR-150 associated with colorectal cancer progression
por: Aherne, Sinéad T, et al.
Publicado: (2015)

Renal inhibition of miR-181a ameliorates 5-fluorouracil-induced mesangial cell apoptosis and nephrotoxicity
por: Liu, Xiao-Yun, et al.
Publicado: (2018)

A miR-192-EGR1-HOXB9 regulatory network controls the angiogenic switch in cancer
por: Wu, Sherry Y., et al.
Publicado: (2016)

miR-34s keep osteoblasts bone idle
por: Short, Ben
Publicado: (2012)

miR-34 modulates wing polyphenism in planthopper
por: Ye, Xinhai, et al.
Publicado: (2019)

Predictive Value of MiR-219-1, MiR-938, MiR-34b/c, and MiR-218 Polymorphisms for Gastric Cancer Susceptibility and Prognosis
por: Wu, Yanhua, et al.
Publicado: (2017)

miR-9, miR-21, miR-27b, and miR-34a Expression in HPV16/58/52-Infected Cervical Cancer
por: Liu, Mi, et al.
Publicado: (2020)

Oligoasthenoteratozoospermia and Infertility in Mice Deficient for miR-34b/c and miR-449 Loci
por: Comazzetto, Stefano, et al.
Publicado: (2014)

Cortical Morphogenesis during Embryonic Development Is Regulated by miR-34c and miR-204
por: Venø, Morten T., et al.
Publicado: (2017)

The miR-34a-LDHA axis regulates glucose metabolism and tumor growth in breast cancer
por: Xiao, Xiangsheng, et al.
Publicado: (2016)

Correlation Between Serum miR-154-5p and Osteocalcin in Males and Postmenopausal Females of Type 2 Diabetes With Different Urinary Albumin Creatinine Ratios
por: Ren, Huiwen, et al.
Publicado: (2019)

A rare SNP in pre-miR-34a is associated with increased levels of miR-34a in pancreatic beta cells
por: Locke, Jonathan M., et al.
Publicado: (2013)

The PBX1/miR-141-miR-200a/EGR2/SOCS3 Axis; Integrative Analysis of Interaction Networks to Discover the Possible Mechanism of MiR-141 and MiR-200a-Mediated Th17 Cell Differentiation
por: Bahmani, Leila, et al.
Publicado: (2023)

miR-34 Modulates Innate Immunity and Ecdysone Signaling in Drosophila
por: Xiong, Xiao-Peng, et al.
Publicado: (2016)

Naringin ameliorates the high glucose-induced rat mesangial cell inflammatory reaction by modulating the NLRP3 Inflammasome
por: Chen, Fenqin, et al.
Publicado: (2018)

Posttranscriptional deregulation of Src due to aberrant miR34a and miR203 contributes to gastric cancer development
por: Hao, Qiang, et al.
Publicado: (2013)

Overcoming melanoma resistance to vemurafenib by targeting CCL2-induced miR-34a, miR-100 and miR-125b
por: Vergani, Elisabetta, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_v3qva9amdtcpfshhf1r83fs0jh