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Using an engineered glutamate-gated chloride channel to silence sensory neurons and treat neuropathic pain at the source

See Basbaum (doi:10.1093/brain/awx227) for a scientific commentary on this article. Peripheral neuropathic pain arises as a consequence of injury to sensory neurons; the development of ectopic activity in these neurons is thought to be critical for the induction and maintenance of such pain. Local a...

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Detalles Bibliográficos
Autores principales: Weir, Greg A, Middleton, Steven J, Clark, Alex J, Daniel, Tarun, Khovanov, Nikita, McMahon, Stephen B, Bennett, David L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841150/
https://www.ncbi.nlm.nih.gov/pubmed/28969375
http://dx.doi.org/10.1093/brain/awx201