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Using an engineered glutamate-gated chloride channel to silence sensory neurons and treat neuropathic pain at the source
See Basbaum (doi:10.1093/brain/awx227) for a scientific commentary on this article. Peripheral neuropathic pain arises as a consequence of injury to sensory neurons; the development of ectopic activity in these neurons is thought to be critical for the induction and maintenance of such pain. Local a...
Autores principales: | Weir, Greg A, Middleton, Steven J, Clark, Alex J, Daniel, Tarun, Khovanov, Nikita, McMahon, Stephen B, Bennett, David L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841150/ https://www.ncbi.nlm.nih.gov/pubmed/28969375 http://dx.doi.org/10.1093/brain/awx201 |
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