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Enhanced Expression of the Key Mitosis Regulator Cyclin B1 Is Mediated by PDZ-Binding Kinase in Islets of Pregnant Mice

The proliferation of pancreatic β cells is enhanced to enable an increase in β-cell mass and to compensate for insulin resistance during pregnancy. To elucidate the mechanisms involved, we previously investigated islets from pregnant and nonpregnant mice by gene expression profiling and found that t...

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Detalles Bibliográficos
Autores principales: Uesato, Tadayoshi, Ogihara, Takeshi, Hara, Akemi, Iida, Hitoshi, Miyatsuka, Takeshi, Fujitani, Yoshio, Takeda, Satoru, Watada, Hirotaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841183/
https://www.ncbi.nlm.nih.gov/pubmed/29594255
http://dx.doi.org/10.1210/js.2017-00338