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Enhanced Expression of the Key Mitosis Regulator Cyclin B1 Is Mediated by PDZ-Binding Kinase in Islets of Pregnant Mice
The proliferation of pancreatic β cells is enhanced to enable an increase in β-cell mass and to compensate for insulin resistance during pregnancy. To elucidate the mechanisms involved, we previously investigated islets from pregnant and nonpregnant mice by gene expression profiling and found that t...
Autores principales: | Uesato, Tadayoshi, Ogihara, Takeshi, Hara, Akemi, Iida, Hitoshi, Miyatsuka, Takeshi, Fujitani, Yoshio, Takeda, Satoru, Watada, Hirotaka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841183/ https://www.ncbi.nlm.nih.gov/pubmed/29594255 http://dx.doi.org/10.1210/js.2017-00338 |
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