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Reduction of Aβ Generation by Schisandrin B through Restraining Beta-Secretase 1 Transcription and Translation
BACKGROUND: Beta-secretase 1 (BACE1) is a rate-limiting enzyme in the generation of amyloid beta peptides, which are associated with Alzheimer’s disease (AD). It has been reported that Schisandrin B could improve cognitive functions in animal models of AD, but the underlying mechanisms are not compl...
Autores principales: | Li, Zeng, Liu, Xiao-chang, Li, Rui, Chang, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841190/ https://www.ncbi.nlm.nih.gov/pubmed/29487280 http://dx.doi.org/10.12659/MSM.905127 |
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