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Human immunodeficiency virus Tat impairs mitochondrial fission in neurons

Human immunodeficiency virus-1 (HIV) infection of the central nervous system promotes neuronal injury that culminates in HIV-associated neurocognitive disorders. Viral proteins, including transactivator of transcription (Tat), have emerged as leading candidates to explain HIV-mediated neurotoxicity,...

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Detalles Bibliográficos
Autores principales: Rozzi, Summer J., Avdoshina, Valeria, Fields, Jerel A., Mocchetti, Italo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841280/
https://www.ncbi.nlm.nih.gov/pubmed/29531805
http://dx.doi.org/10.1038/s41420-017-0013-6