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Lithium induces mesenchymal-epithelial differentiation during human kidney development by activation of the Wnt signalling system

Kidney function is directly linked to the number of nephrons which are generated until 32–36 weeks gestation in humans. Failure to make nephrons during development leads to congenital renal malformations, whilst nephron loss in adulthood occurs in progressive renal disease. Therefore, an understandi...

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Detalles Bibliográficos
Autores principales: Price, Karen L., Kolatsi-Joannou, Maria, Mari, Chiara, Long, David A., Winyard, Paul J. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841285/
https://www.ncbi.nlm.nih.gov/pubmed/29531810
http://dx.doi.org/10.1038/s41420-017-0021-6