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Lithium induces mesenchymal-epithelial differentiation during human kidney development by activation of the Wnt signalling system
Kidney function is directly linked to the number of nephrons which are generated until 32–36 weeks gestation in humans. Failure to make nephrons during development leads to congenital renal malformations, whilst nephron loss in adulthood occurs in progressive renal disease. Therefore, an understandi...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841285/ https://www.ncbi.nlm.nih.gov/pubmed/29531810 http://dx.doi.org/10.1038/s41420-017-0021-6 |