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Image-Guided Focused-Ultrasound CNS Molecular Delivery: An Implementation via Dynamic Contrast-Enhanced Magnetic-Resonance Imaging

Focused ultrasound (FUS) exposure with microbubbles can transiently open the blood-brain barrier (BBB) to deliver therapeutic molecules into CNS tissues. However, delivered molecular distribution/concentration at the target need to be controlled. Dynamic Contrast-Enhanced Magnetic-Resonance Imaging...

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Detalles Bibliográficos
Autores principales: Chai, Wen-Yen, Chu, Po-Chun, Tsai, Chih-Hung, Lin, Chung-Yin, Yang, Hung-Wei, Lai, Hsin-Yi, Liu, Hao-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841286/
https://www.ncbi.nlm.nih.gov/pubmed/29515222
http://dx.doi.org/10.1038/s41598-018-22571-8