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Image-Guided Focused-Ultrasound CNS Molecular Delivery: An Implementation via Dynamic Contrast-Enhanced Magnetic-Resonance Imaging
Focused ultrasound (FUS) exposure with microbubbles can transiently open the blood-brain barrier (BBB) to deliver therapeutic molecules into CNS tissues. However, delivered molecular distribution/concentration at the target need to be controlled. Dynamic Contrast-Enhanced Magnetic-Resonance Imaging...
Autores principales: | Chai, Wen-Yen, Chu, Po-Chun, Tsai, Chih-Hung, Lin, Chung-Yin, Yang, Hung-Wei, Lai, Hsin-Yi, Liu, Hao-Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841286/ https://www.ncbi.nlm.nih.gov/pubmed/29515222 http://dx.doi.org/10.1038/s41598-018-22571-8 |
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