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PLEKHN1 promotes apoptosis by enhancing Bax-Bak hetro-oligomerization through interaction with Bid in human colon cancer

The anti-apoptotic nature of cancer cells often impedes the effects of anti-cancer therapeutic agents. Multiple death signals influence mitochondria during apoptosis, and though many studies have attempted to elucidate these complicated pathways, Bax oligomerization, an important step in the process...

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Detalles Bibliográficos
Autores principales: Kuriyama, Sei, Tsuji, Tadahiro, Sakuma, Tetsushi, Yamamoto, Takashi, Tanaka, Masamistu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841295/
https://www.ncbi.nlm.nih.gov/pubmed/29531808
http://dx.doi.org/10.1038/s41420-017-0006-5