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FOXO3-dependent apoptosis limits alcohol-induced liver inflammation by promoting infiltrating macrophage differentiation

Alcohol consumption is generally well tolerated by the liver but in some individuals it results in persistent inflammation and liver disease. The mechanisms that regulate alcohol-induced liver inflammation are poorly understood. The transcription factor FOXO3 has previously been shown to be involved...

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Detalles Bibliográficos
Autores principales: Li, Zhuan, Zhao, Jie, Zhang, Shujun, Weinman, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841311/
https://www.ncbi.nlm.nih.gov/pubmed/29531813
http://dx.doi.org/10.1038/s41420-017-0020-7