NR4A2 protects cardiomyocytes against myocardial infarction injury by promoting autophagy

Myocardial infarction (MI), characterized by ischemia-induced cardiomyocyte apoptosis, is the leading cause of mortality worldwide. NR4A2, a member of the NR4A orphan nucleus receptor family, is upregulated in mouse hearts with MI injury. Furthermore, NR4A2 knockdown aggravates heart injury as evide...

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Detalles Bibliográficos
Autores principales: Liu, Honghong, Liu, Pingping, Shi, Xingxing, Yin, Deling, Zhao, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841341/
https://www.ncbi.nlm.nih.gov/pubmed/29531824
http://dx.doi.org/10.1038/s41420-017-0011-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841341/
https://www.ncbi.nlm.nih.gov/pubmed/29531824
http://dx.doi.org/10.1038/s41420-017-0011-8

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