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NR4A2 protects cardiomyocytes against myocardial infarction injury by promoting autophagy
Myocardial infarction (MI), characterized by ischemia-induced cardiomyocyte apoptosis, is the leading cause of mortality worldwide. NR4A2, a member of the NR4A orphan nucleus receptor family, is upregulated in mouse hearts with MI injury. Furthermore, NR4A2 knockdown aggravates heart injury as evide...
Autores principales: | Liu, Honghong, Liu, Pingping, Shi, Xingxing, Yin, Deling, Zhao, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841341/ https://www.ncbi.nlm.nih.gov/pubmed/29531824 http://dx.doi.org/10.1038/s41420-017-0011-8 |
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