Cortactin regulates endo-lysosomal sorting of AMPARs via direct interaction with GluA2 subunit

AMPA receptor (AMPAR) trafficking is a key determinant of synaptic strength and synaptic plasticity. Under basal conditions, constitutive trafficking maintains surface AMPARs by internalization into the endosomal system, where the majority are sorted and targeted for recycling back to the plasma mem...

Descripción completa

Detalles Bibliográficos
Autores principales: Parkinson, Gabrielle T., Chamberlain, Sophie E. L., Jaafari, Nadia, Turvey, Matthew, Mellor, Jack R., Hanley, Jonathan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841360/
https://www.ncbi.nlm.nih.gov/pubmed/29515177
http://dx.doi.org/10.1038/s41598-018-22542-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841360/
https://www.ncbi.nlm.nih.gov/pubmed/29515177
http://dx.doi.org/10.1038/s41598-018-22542-z

Ejemplares similares