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A dual-function epidermal growth factor receptor pathway substrate 8 (Eps8)-derived peptide exhibits a potent cytotoxic T lymphocyte-activating effect and a specific inhibitory activity

The identification and characterization of tumor-associated antigens (TAAs) that generate specific cytotoxic T lymphocytes (CTLs) are vital to the development of cancer immunotherapy. The epidermal growth factor receptor (EGFR) pathway substrate 8 gene (Eps8) is involved in regulating cancer progres...

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Detalles Bibliográficos
Autores principales: Xie, Xiaoling, Zhou, Weijun, Hu, Yuxing, Chen, Yiran, Zhang, Honghao, Li, Yuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841361/
https://www.ncbi.nlm.nih.gov/pubmed/29515106
http://dx.doi.org/10.1038/s41419-018-0420-5