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Raddeanin A suppresses breast cancer-associated osteolysis through inhibiting osteoclasts and breast cancer cells

Bone metastasis is a severe complication of advanced breast cancer, resulting in osteolysis and increased mortality in patients. Raddeanin A (RA), isolated from traditional Chinese herbs, is an oleanane-type triterpenoid saponin with anticancer potential. In this study, we investigated the effects o...

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Detalles Bibliográficos
Autores principales: Wang, Qiang, Mo, Jian, Zhao, Chenchen, Huang, Kangmao, Feng, Mingxuan, He, Wenxin, Wang, Jiying, Chen, Shuai, Xie, Zi’ang, Ma, Jianjun, Fan, Shunwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841366/
https://www.ncbi.nlm.nih.gov/pubmed/29515110
http://dx.doi.org/10.1038/s41419-018-0417-0