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Influence of Effective Population Size on Genes under Varying Levels of Selection Pressure

The ratio of diversities at amino acid changing (nonsynonymous) and neutral (synonymous) sites (ω = π(N)/π(S)) is routinely used to measure the intensity of selection pressure. It is well known that this ratio is influenced by the effective population size (N(e)) and selection coefficient (s). Here,...

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Detalles Bibliográficos
Autor principal: Subramanian, Sankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841380/
https://www.ncbi.nlm.nih.gov/pubmed/29608718
http://dx.doi.org/10.1093/gbe/evy047