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Quantitative peptidomics of endogenous peptides involved in TGF-β1-induced epithelial mesenchymal transition of renal epithelial cells

TGF-β1 is a key fibrotic factor mediating epithelial mesenchymal transition (EMT) of epithelial cells through various signaling pathways. However, roles of proteolytic cleavage and endogenous peptide dynamics in TGF-β1-induced EMT remain unknown. We therefore performed quantitative peptidomics of TG...

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Detalles Bibliográficos
Autores principales: Kanlaya, Rattiyaporn, Thongboonkerd, Visith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841401/
https://www.ncbi.nlm.nih.gov/pubmed/29531806
http://dx.doi.org/10.1038/s41420-017-0001-x