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Suppressing IL-36-driven inflammation using peptide pseudosubstrates for neutrophil proteases
Sterile inflammation is initiated by molecules released from necrotic cells, called damage-associated molecular patterns (DAMPs). Members of the extended IL-1 cytokine family are important DAMPs, are typically only released through necrosis, and require limited proteolytic processing for activation....
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841435/ https://www.ncbi.nlm.nih.gov/pubmed/29515113 http://dx.doi.org/10.1038/s41419-018-0385-4 |