Cargando…
Suppressing IL-36-driven inflammation using peptide pseudosubstrates for neutrophil proteases
Sterile inflammation is initiated by molecules released from necrotic cells, called damage-associated molecular patterns (DAMPs). Members of the extended IL-1 cytokine family are important DAMPs, are typically only released through necrosis, and require limited proteolytic processing for activation....
Autores principales: | Sullivan, Graeme P., Henry, Conor M., Clancy, Danielle M., Mametnabiev, Tazhir, Belotcerkovskaya, Ekaterina, Davidovich, Pavel, Sura-Trueba, Sylvia, Garabadzhiu, Alexander V., Martin, Seamus J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841435/ https://www.ncbi.nlm.nih.gov/pubmed/29515113 http://dx.doi.org/10.1038/s41419-018-0385-4 |
Ejemplares similares
-
Identification of small‐molecule elastase inhibitors as antagonists of IL‐36 cytokine activation
por: Sullivan, Graeme P., et al.
Publicado: (2018) -
Production of biologically active IL‐36 family cytokines through insertion of N‐terminal caspase cleavage motifs
por: Clancy, Danielle M., et al.
Publicado: (2016) -
IL-1α and IL-36 Family Cytokines Can Undergo Processing and Activation by Diverse Allergen-Associated Proteases
por: Frezza, Valentina, et al.
Publicado: (2022) -
Broadband Ge/SiGe quantum dot photodetector on pseudosubstrate
por: Yakimov, Andrew, et al.
Publicado: (2013) -
A Stapled Peptide Mimic of the Pseudosubstrate Inhibitor PKI Inhibits Protein Kinase A
por: Manschwetus, Jascha T., et al.
Publicado: (2019)