Biological Significance of the Suppression of Oxidative Phosphorylation in Induced Pluripotent Stem Cells

We discovered that induced pluripotent stem cell (iPSC) clones generated from aged tissue donors (A-iPSCs) fail to suppress oxidative phosphorylation. Compared to embryonic stem cells (ESCs) and iPSCs generated from young donors (Y-iPSCs), A-iPSCs show poor expression of the pluripotent stem cell-sp...

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Detalles Bibliográficos
Autores principales: Zhang, Cheng, Skamagki, Maria, Liu, Zhong, Ananthanarayanan, Aparna, Zhao, Rui, Li, Hu, Kim, Kitai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841608/
https://www.ncbi.nlm.nih.gov/pubmed/29166598
http://dx.doi.org/10.1016/j.celrep.2017.10.098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841608/
https://www.ncbi.nlm.nih.gov/pubmed/29166598
http://dx.doi.org/10.1016/j.celrep.2017.10.098

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