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Biological Significance of the Suppression of Oxidative Phosphorylation in Induced Pluripotent Stem Cells

We discovered that induced pluripotent stem cell (iPSC) clones generated from aged tissue donors (A-iPSCs) fail to suppress oxidative phosphorylation. Compared to embryonic stem cells (ESCs) and iPSCs generated from young donors (Y-iPSCs), A-iPSCs show poor expression of the pluripotent stem cell-sp...

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Detalles Bibliográficos
Autores principales:	Zhang, Cheng, Skamagki, Maria, Liu, Zhong, Ananthanarayanan, Aparna, Zhao, Rui, Li, Hu, Kim, Kitai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841608/ https://www.ncbi.nlm.nih.gov/pubmed/29166598 http://dx.doi.org/10.1016/j.celrep.2017.10.098

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