Retinal guanylyl cyclase activating protein 1 forms a functional dimer

Retinal guanylyl cyclases (RetGCs) in vertebrate photoreceptors are regulated by the guanylyl cyclase activator proteins (GCAP1 and GCAP2). Here, we report EPR double electron-electron resonance (DEER) studies on the most ubiquitous GCAP isoform, GCAP1 and site-directed mutagenesis analysis to deter...

Descripción completa

Detalles Bibliográficos
Autores principales: Lim, Sunghyuk, Roseman, Graham, Peshenko, Igor, Manchala, Grace, Cudia, Diana, Dizhoor, Alexander M., Millhauser, Glenn, Ames, James B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841803/
https://www.ncbi.nlm.nih.gov/pubmed/29513743
http://dx.doi.org/10.1371/journal.pone.0193947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841803/
https://www.ncbi.nlm.nih.gov/pubmed/29513743
http://dx.doi.org/10.1371/journal.pone.0193947

Ejemplares similares