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Retinal guanylyl cyclase activating protein 1 forms a functional dimer
Retinal guanylyl cyclases (RetGCs) in vertebrate photoreceptors are regulated by the guanylyl cyclase activator proteins (GCAP1 and GCAP2). Here, we report EPR double electron-electron resonance (DEER) studies on the most ubiquitous GCAP isoform, GCAP1 and site-directed mutagenesis analysis to deter...
Autores principales: | Lim, Sunghyuk, Roseman, Graham, Peshenko, Igor, Manchala, Grace, Cudia, Diana, Dizhoor, Alexander M., Millhauser, Glenn, Ames, James B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841803/ https://www.ncbi.nlm.nih.gov/pubmed/29513743 http://dx.doi.org/10.1371/journal.pone.0193947 |
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