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A multiscale modelling approach to assess the impact of metabolic zonation and microperfusion on the hepatic carbohydrate metabolism

The capacity of the liver to convert the metabolic input received from the incoming portal and arterial blood into the metabolic output of the outgoing venous blood has three major determinants: The intra-hepatic blood flow, the transport of metabolites between blood vessels (sinusoids) and hepatocy...

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Detalles Bibliográficos
Autores principales: Berndt, Nikolaus, Horger, Marius Stefan, Bulik, Sascha, Holzhütter, Hermann-Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841820/
https://www.ncbi.nlm.nih.gov/pubmed/29447152
http://dx.doi.org/10.1371/journal.pcbi.1006005