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A multiscale modelling approach to assess the impact of metabolic zonation and microperfusion on the hepatic carbohydrate metabolism
The capacity of the liver to convert the metabolic input received from the incoming portal and arterial blood into the metabolic output of the outgoing venous blood has three major determinants: The intra-hepatic blood flow, the transport of metabolites between blood vessels (sinusoids) and hepatocy...
Autores principales: | Berndt, Nikolaus, Horger, Marius Stefan, Bulik, Sascha, Holzhütter, Hermann-Georg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841820/ https://www.ncbi.nlm.nih.gov/pubmed/29447152 http://dx.doi.org/10.1371/journal.pcbi.1006005 |
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