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Distinct susceptibility of HIV vaccine vector-induced CD4 T cells to HIV infection

The concerns raised from adenovirus 5 (Ad5)-based HIV vaccine clinical trials, where excess HIV infections were observed in some vaccine recipients, have highlighted the importance of understanding host responses to vaccine vectors and the HIV susceptibility of vector-specific CD4 T cells in HIV vac...

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Detalles Bibliográficos
Autores principales: Auclair, Sarah, Liu, Fengliang, Niu, Qingli, Hou, Wei, Churchyard, Gavin, Morgan, Cecilia, Frahm, Nicole, Nitayaphan, Sorachai, Pitisuthithum, Punnee, Rerks-Ngarm, Supachai, Kimata, Jason T., Soong, Lynn, Franchini, Genoveffa, Robb, Merlin, Kim, Jerome, Michael, Nelson, Hu, Haitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841825/
https://www.ncbi.nlm.nih.gov/pubmed/29474461
http://dx.doi.org/10.1371/journal.ppat.1006888